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Stoke Therapeutics, Inc.

STOK

Last
$24.74
Day
+3.3%
1y
-19.9%
5y
-7.4%
52w
-40.5%
SPY YTD
+13.3%
XLV
+8.1%
Earnings
2026-11-0323d
EMA 21
26.33
EMA 50
28.26
EMA 200
29.21
20d high
-19.4%
5y high
-40.5%
5y range
56th
Website · 170 employees · United States

Positions held

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Score
-24
Hold
avoid
Signal
Strong Sell
Target
$26.21
Stop
$22.06
Stop distance
10.8%
Target vs last
+5.9%

Bull / bear case

Site-generated summary from fundamentals, news, and score — not investment advice. As of 2026-10-08.

Bull case
  • Stoke Therapeutics is positioned in the biotechnology industry, focusing on innovative therapies that address unmet medical needs, which can attract significant investor interest.
  • Revenue increased by 50% compared to the prior quarter, reaching $9.3 million.
  • The operating margin improved to -701.7%, indicating potential for future operational efficiencies.
Bear case
  • The company is currently facing challenges with a negative profit margin and significant operating losses, which raises concerns about its financial health.
  • Stoke's revenue growth has been declining, with a yearly revenue of only $8.78 million in 2023.
  • The stock has a strong sell signal with a score of -24.00, indicating bearish market sentiment.

Fundamentals

Market cap$1.55BEnterprise value$1.26BTrailing P/E—Forward P/E-6.81
PEG—Price / book4.33Beta1.26Dividend yield0.00%
Revenue growth-32.5%Earnings growth—Gross margin100.0%Operating margin-7.0%
Profit margin0.0%ROE-61.1%ROA-35.9%Debt / equity0.01
Current ratio7.69Free cash flow-$106.20MAnalyst recommendationstrong_buyMean target$46.46
52w high$40.2252w low$20.32

Quarterly

2026-Q22026-Q12025-Q42025-Q32025-Q22025-Q1
Revenue$9.3M$6.2M$1.4M$10.6M$13.8M—
Op margin-701.7%-857.6%-4382.2%-405.3%-197.6%—
Net income-$61.6M-$50.0M-$57.9M-$38.3M-$23.5M—
Gross margin——————
Gross profit——————
Operating income-$65.4M-$53.4M-$61.4M-$43.1M-$27.3M—
  • Revenue +50% vs prior quarter ($9.3M vs $6.2M).
  • Operating margin expanded to -701.7%.

Yearly (6y)

20252024202320222021
Revenue$184M$36.6M$8.8M$12.4M—
Op margin-11.2%-277.3%-1307.2%-841.2%—
Net income-$6.9M-$89.0M-$105M-$101M—
Gross margin—————
Gross profit—————
Operating income-$20.6M-$101M-$115M-$104M—
Headline scan

No flags

• No distress or material-risk keywords in recent headlines (keyword scan only — not a guarantee).

News

2026-10-06 · Stoke Therapeutics Announces Presentations of STK-002, an Investigational Medicine for the Treatment of Autosomal Dominant Optic Atrophy (ADOA), at the American Academy of Ophthalmology (AAO) 2026 Annual Meeting

2026-10-05 · Stoke Therapeutics Completes FDA Meeting on Planned Zorevunersen NDA

2026-10-05 · Stoke Therapeutics Announces Completion of Successful Meeting with the FDA to Align on Planned U.S. NDA for Zorevunersen, an Investigational Medicine for the Treatment of Dravet Syndrome

2026-09-23 · Stoke Therapeutics Appoints Bo Cumbo to its Board of Directors, Enhancing Commercial Expertise as the Company Advances Zorevunersen Development Toward Potential FDA Approval and Commercialization

2026-09-16 · Stoke Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(C)(4)

2026-09-03 · Stoke Therapeutics and Biogen Present Long-Term Clinical Data that Support the Disease-Modifying Potential of Zorevunersen, an Investigational Medicine for the Treatment of Dravet Syndrome, at the 16th European Epilepsy Congress (EEC)

2026-09-03 · Stoke Therapeutics and Biogen Present Long-Term Clinical Data that Support the Disease-Modifying Potential of Zorevunersen, an Investigational Medicine for the Treatment of Dravet Syndrome, at the 16th European Epilepsy Congress (EEC)

2026-09-02 · Stoke Therapeutics to Present at the Cantor Global Healthcare Conference

2026-09-01 · Stoke Therapeutics and Biogen Announce Presentations of Clinical Data from Studies of Zorevunersen, an Investigational Medicine for the Treatment of Dravet Syndrome, at the 16th European Epilepsy Congress (EEC)

2026-09-01 · Stoke Therapeutics and Biogen Announce Presentations of Clinical Data from Studies of Zorevunersen, an Investigational Medicine for the Treatment of Dravet Syndrome, at the 16th European Epilepsy Congress (EEC)

2026-08-21 · Stoke Therapeutics shares rise as JPMorgan starts coverage with Overweight rating

2026-08-18 · Stoke Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(C)(4)

STOK · daily-18.0% over 13 sessions
Close EMA21 EMA50 EMA200
22.6824.4426.2027.9629.722026-092026-092026-092026-092026-102026-102026-10
Quarterly · revenue, net income, margins
Revenue Net income Gross margin Op margin
-$62M-$43M-$24M-$5M$14M-4382%-2186%10%2025-Q22025-Q32025-Q42026-Q12026-Q2